That is arguably the most famous anti-drug commercial ever made. But was it effective?

I asked Keith Humpreys, professor at the Stanford School Of Medicine, who has reviewed lots of studies about all sorts of anti-drug ads — and the results might surprise you. We talked about what worked, what didn’t, and what was wrong with the messaging.

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There’s also this, a brilliant parody of another ad produced by the White House Office of National Drug Control Policy. It starts with the original version, starring actress Rachel Leigh Cook, then extends it with a lookalike and a few family members…